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The principal cytochrome P450 isoenzyme associated appears to get CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Roughly 85% of an oral dose appears within the urine inside of 24 several hours of administration, most as the glucuronide conjugate, with tiny quantities of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity information